Often an otherwise effective drug does not treat a disease, because a specific strain is not responding to that treatment. For example, there are dozens of anti-tuberculous drugs. Because tuberculous tests cannot identify the strain, patients can end up trying one drug after another, often over the course of weeks or months before a cure can be found. Major differentiators of SnapDNA include DNA detection at the specificity level of microbial strain in a field deployable instrument that is expected to enable rapid, strain-specific, low cost, POC testing for tuberculous, pneumonia, and other drug resistant strains that may lead to sepsis.